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Can AI Run a Drug Discovery Lab on Its Own?

1What It Would Mean for AI to Run a Lab2The Drug Discovery Pipeline in Plain Terms3Where AI Already Helps Today4Closing the Loop: Self-Driving Labs5Real Examples of AI-Run Lab Systems6Where Autonomy Breaks Down7What Still Needs a Human
Where Autonomy Breaks Down

Clean Data, Messy Biology

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A closed-loop system learns from data, and the data it learns from is curated. Measurements are cleaned, labeled, and lined up so that the same input always means the same thing.
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AI models for drug discovery are trained on curated datasets where measurements are consistent, labeled, and comparable. Real biological measurements are not like that. The same sample can read differently across days, instruments, and labs; cell lines drift; assays vary in sensitivity; and results are often recorded in inconsistent formats. This mismatch is a structural limit, not a temporary one: a model that learned from a tidy table meets a world that does not produce tidy tables.

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